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Student Research Guide: Anxiety and Medicinal Cannabis: Top 10 Resources

By Kelsey McKinney, Fall 2020, LIB 201

Top 10 Resources

Corroon,James M.,,Jr, Laurie K. Mischley, and Michelle Sexton. "Cannabis as a Substitute for Prescription Drugs – a Cross-Sectional Study." Journal of Pain Research, vol. 10, 2017, pp. 989-998. ProQuest,, doi:

  • This study focuses on the use of cannabis as a substitution for prescription drugs in order to treat impairments like pain, anxiety, and depression. The study also aims to understand the correlation between the rates that people are substituting cannabis for prescription drugs and the rates that the usage and abuse of prescription drugs are decreasing in states that have legalized medicinal marijuana. I chose this source for my Research Guide because I found that it gave great incite into the relationship between medicinal cannabis and anxiety, but also the rate at which the use and abuse of prescription drugs is decreasing due to the legalization of medicinal marijuana.

García-Gutiérrez, María S., et al. “Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders.” Biomolecules (2218-273X), vol. 10, no. 11, Nov. 2020, p. 1575. EBSCOhost, doi:10.3390/biom10111575.

  • This article looks into cannabidiol (CBD), which is a chemical in the cannabis sativa plant, and studies the anti-anxiety, anti-depressant, and anti-psychotic affects that CBD is shown to provide for its users, while also being a drug without the potential for abuse. I chose this source for my Research Guide because it provides detailed information on the anti-anxiety affects that CBD can have on its user, it shows the drug in comparison to others of similar popularity and source, and it gives a deeper understanding of the beneficial and disadvantageous aspects of CBD.

Hoch, Eva, et al. “How Effective and Safe Is Medical Cannabis as a Treatment of Mental Disorders? A Systematic Review.” European Archives of Psychiatry & Clinical Neuroscience, vol. 269, no. 1, Feb. 2019, pp. 87–105. EBSCOhost, doi:10.1007/s00406-019-00984-4.

  • This systematic review's goal was to further understand the effectiveness and safety of medicinal cannabis as a treatment of a multitude of mental disorders, one of them being general social anxiety. This review created trials in order to understand the effectiveness and safety of medicinal cannabis, both THC and CBD-based medicines, and concluded that while side affects occurred, this study needs larger scale trials and more research before providing reliable treatment. I liked this source for my topic because it provided a systematic review that included trials of testing two different forms of cannabis-sourced medicines, and gave further research to the effectiveness in treatment that cannabis may provide for mental disorders, including general social anxiety disorder.

de Mello Schier, Alexandre Rafael, et al. “Cannabidiol, a Cannabis Sativa Constituent, as an Anxiolytic Drug.” Revista Brasileira de Psiquiatria, vol. 34, no. S1, June 2012, pp. S104–S110. EBSCOhost, doi:10.1016/S1516-4446(12)70057-0.

  • The purpose of this article is to review and describe the effects of cannabidiol (CBD) as an anti-anxiety drug, and discuss what this drug could be best used for, and put together a host of articles full of research and studies that showed the effects of CBD on animal and human subjects. This article found that CBD did in fact have anti-anxiety properties, specifically in subjects with social anxiety disorder, but concluded that more studies and research should be done on CBD's properties before considered an effective treatment. I found this article to be very informational specifically for my topic as it discusses the direct relationship between anxiety and cannabis-based drugs, and whether it is or could be considered an effective treatment for anxiety disorders.

Rosenberg, Loflin. “Prescribing Health Care Providers’ Attitudes, Experiences, and Practices Surrounding Cannabis Use in Patients with Anxiety Disorders and Post-Traumatic Stress Disorder.” Cannabis and Cannabinoid Research, vol. 4, no. 2, Mary Ann Liebert, Inc., publishers, June 2019, pp. 124–30, doi:10.1089/can.2018.0008.

  • This study's main focus is the perspectives of health care providers' in regards to cannabis use for patients with anxiety disorders and PTSD. Most healthcare providers in the study found that cannabinoids have shown to benefit patients with said disorders, however most of the providers still would not recommend the use of cannabis to their patients for those disorders, and feel that their needs to be more research done for cannabis as a treatment for mental disorders before even considering it as a treatment. I found this study beneficial for my topic because it provides the professional standpoint of health care providers themselves and gives their perspectives on cannabis as an effective treatment for anxiety disorders.

Sarris, Jerome, et al. "Medicinal Cannabis for Psychiatric Disorders: A Clinically-Focused Systematic Review." BMC Psychiatry, vol. 20, 2020, pp. 1-14. ProQuest,, doi:

  • This systematic review focuses on the potential for cannabis-based drugs/medicines to become a treatment for a multitude of psychiatric disorders, while extensive research has been done for cannabis treatment in terms of physical ailments, the psychiatric field has significantly less studies and research done for this type of treatment. Certain cannabis-based medicines have proven to show beneficial results for some psychiatric disorder, however disorders such as depression have seen no efficacy thus far, and the review concludes that, while cannabis-bases medicine has bright potential, more research must be done before it is considered an effective treatment. I liked this source for my Guide because it gave a general idea of psychiatric disorders that have or haven't seen beneficial effects from cannabis-based medicines, one of which was social anxiety disorder that saw beneficial effects from the drug(s), and gave more insight into what could be done with this information and what the psychiatric field can expand on with this research.

Shannon, Scott. “Cannabidiol in Anxiety and Sleep: A Large Case Series.” Permanente Journal, vol. 23, The Permanente Press, 2019, pp. 18–041, doi:10.7812/tpp/18-041.

  • This study's aim was to understand and determine whether CBD had an affect on anxiety and sleep, as there has been more and more pre-clinical and clinical evidence that suggests that CBD may have some value and provide benefits for neuropsychiatric disorders, anxiety being one of them. Ultimately the study concluded that cannabidiol has been seen to provide potential benefits for anxiety-related disorders, varied results with sleep aid, and overall still needs much more research and studies conducted to provide more substantive evidence for cannabidiol as a treatment for anxiety. I found this study to relate to my topic well because it shows a direct relationship between cannabidiol and anxiety symptoms, and provides more information on the rates at which it was effective for the case study conducted on anxiety and sleep.

Troup, Lucy J et al. “The relationship between cannabis use and measures of anxiety and depression in a sample of college campus cannabis users and non-users post state legalization in Colorado.” PeerJ, vol. 4 e2782. 8 Dec. 2016, doi:10.7717/peerj.2782.

  • This study focuses on the relationship cannabis use and measures of anxiety and depression in college students after cannabis legalization in Colorado, providing evidence that there is a relationship between high depression levels and cannabis use, but no apparent relationship between anxiety and cannabis use among this participant group. I found this source useful for my Research Guide because it gives a study of the effects on participants of varying degrees of cannabis usage on their depression and anxiety and levels, and shows no relationship towards anxiety levels in this case. 

Turna, Simpson. “Cannabis Use Behaviors and Prevalence of Anxiety and Depressive Symptoms in a Cohort of Canadian Medicinal Cannabis Users.” Journal of Psychiatric Research, vol. 111, Elsevier BV, Apr. 2019, pp. 134–39, doi:10.1016/j.jpsychires.2019.01.024.

  • The purpose of this study was to analyze the prevalence of cannabis for medical purposes (CMP) use for a variety of anxiety disorders/symptoms as well as depressive disorder/symptoms. This study concluded that most participants noted that CMP seemed to improve symptoms for the listed disorders, however there were certain factors that could not fully be ruled out and more research and studies should/need to be done in order to gain more conclusive evidence. I found this source to be well-related to my Research Guide topic as it provides a case study of subjects with anxiety disorders/anxiety symptoms and what the results of their cannabis use did for those symptoms as well.

Wallis, Aaron L., et al. “Assessing Marijuana Use, Anxiety, and Academic Performance Among College Students.” Journal of College Counseling, vol. 22, no. 2, July 2019, pp. 125–137. EBSCOhost, doi:10.1002/jocc.12125.

  • This article looks at the relationship between college students marijuana use and their anxiety, as well as the affect cannabis use seems to have on their GPA. The results provided in the studies within the article show that cannabis use among college students with anxiety and no formal treatment negatively impacts their GPA, however the results could be impacted in a number of ways. I found this article to be beneficial for my topic because it provides another perspective of marijuana use among subjects with anxiety and how it can impact other aspects of their lives, outside of their anxiety.
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